Complementary Health Approaches

Frequently Asked Questions

20. What has NIH-sponsored research shown about the use of glucosamine and chondroitin for osteoarthritis?

A major NIH-sponsored trial of glucosamine and chondroitin in people with knee osteoarthritis (called GAIT, for Glucosamine/Chondroitin Arthritis Intervention Trial), showed that these supplements did not relieve pain or slow joint damage in the overall group of study participants. However, a subgroup of participants with moderate-to-severe pain did have significant pain relief when they took both supplements in combination.