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Glaucoma

Glaucoma Defined

Glaucoma is a group of diseases that can damage the eye's optic nerve and result in vision loss and blindness. While glaucoma can strike anyone, the risk is much greater for people over 60.

What is Glaucoma?There are several different types of glaucoma. Most of these involve the drainage system within the eye. At the front of the eye there is a small space called the anterior chamber. A clear fluid flows through this chamber and bathes and nourishes the nearby tissues.

In glaucoma, for still unknown reasons, the fluid drains too slowly out of the eye. As the fluid builds up, the pressure inside the eye rises. Unless this pressure is controlled, it may cause damage to the optic nerve and other parts of the eye and result in loss of vision.

Eye anatomyThe most common type of glaucoma is called open-angle glaucoma. In the normal eye, the clear fluid leaves the anterior chamber at the open angle where the cornea and iris meet. When fluid reaches the angle, it flows through a spongy meshwork, like a drain, and leaves the eye.

Open-angle glaucomaSometimes, when the fluid reaches the angle, it passes too slowly through the meshwork drain, causing the pressure inside the eye to build. If the pressure damages the optic nerve, open-angle glaucoma -- and vision loss -- may result.

There is no cure for glaucoma. Vision lost from the disease cannot be restored. However, there are treatments that may save remaining vision. That is why early diagnosis is important.

Quiz

1. There

A. is one type of glaucoma.
B. are two types of glaucoma.
C. are several types of glaucoma.

C is the correct answer. There are several different types of glaucoma. However, the most common type is open-angle glaucoma.

2. Open-angle glaucoma is caused by

A. a decreased pressure in the eye.
B. an increased pressure in the eye.
C. getting something in your eye.

B is the correct answer. Open-angle glaucoma is caused by an increased pressure in the eye that comes from a buildup of fluid in the eye's anterior chamber. Unless this pressure is controlled, it may cause damage to the optic nerve and other parts of the eye and loss of vision.

3. Glaucoma is most common

A. among teenagers.
B. among people in their thirties.
C. among people over age 60.

C is the correct answer. While glaucoma can strike anyone, the risk is much greater for people over 60.

4. Glaucoma

A. can be cured.
B. cannot yet be cured.
C. cannot be treated.

B is the correct answer. There is not yet a cure for glaucoma. Vision lost from the disease cannot be restored. However, there are treatments that may save remaining vision. That is why early diagnosis is important.


Causes and Risk Factors

Nearly 2.2 million people have glaucoma, a leading cause of blindness in the United States. Although anyone can get glaucoma, some people are at higher risk. They include

  • African-Americans over age 40
  • everyone over age 60, especially Mexican-Americans
  • people with a family history of glaucoma.

Studies show that glaucoma is

  • five times more likely to occur in African-Americans than in whites
  • about four times more likely to cause blindness in African-Americans than in whites
  • fifteen times more likely to cause blindness in African Americans between the ages of 45-64 than in whites of the same age group.
Quiz

1. Glaucoma

A. never causes blindness.
B. rarely leads to blindness.
C. is a leading cause of blindness.

C is the correct answer. Glaucoma is a leading cause of blindness and visual impairment, affecting as many as 2.2 million people in the U.S.

2. You are at risk of developing glaucoma if you

A. have a family history of glaucoma.
B. have no family history of glaucoma.
C. get frequent colds.

A is the correct answer. People with a family history of glaucoma are at higher risk for developing the disease.

3. You have a higher risk of developing glaucoma

A. if you are under age 50.
B. if you are under age 40.
C. if you are over age 60.

C is the correct answer. You have higher risk of developing glaucoma if you are over 60 years of age.

4. African-Americans are

A. twice as likely to get glaucoma than whites.
B. five times more likely to get glaucoma than whites.
C. less likely to get glaucoma than whites.

B is the correct answer. Glaucoma is five times more likely to occur in African-Americans than whites, about four times more likely to cause blindness in African-Americans than in whites, and fifteen times more likely to cause blindness in African-Americans between the ages of 45 to 64 than in whites of the same age group.


Symptoms and Diagnosis

Glaucoma can develop in one or both eyes. The most common type of glaucoma, open-angle glaucoma, has no symptoms at first. It causes no pain, and vision seems normal.

Without treatment, people with glaucoma will slowly lose their peripheral, or side vision. They seem to be looking through a tunnel. Over time, straight-ahead vision may decrease until no vision remains.

Glaucoma is detected through a comprehensive eye exam that includes a visual acuity test, visual field test, dilated eye exam, tonometry, and pachymetry.

A visual acuity test uses an eye chart test to measure how well you see at various distances.

A visual field test measures your side or peripheral vision. It helps your eye care professional tell if you have lost side vision, a sign of glaucoma.

In a dilated eye exam, drops are placed in your eyes to widen, or dilate, the pupils. Your eye care professional uses a special magnifying lens to examine your retina and optic nerve for signs of damage and other eye problems. After the exam, your close-up vision may remain blurred for several hours.

TonometryIn tonometry, an instrument measures the pressure inside the eye. Numbing drops may be applied to your eye for this test.

With pachymetry, a numbing drop is applied to your eye. Your eye care professional uses an ultrasonic wave instrument to measure the thickness of your cornea.

Quiz

1. Which of the following is an early sign of open-angle glaucoma?

A. pain
B. redness of the eye
C. loss of central vision
D. none of the above

D is the correct answer. At first, open-angle glaucoma has no symptoms. It causes no pain. Vision seems normal.

2. Glaucoma is detected during a comprehensive eye exam that includes

A. a visual acuity test.
B. a dilated eye exam.
C. a visual field test.
D. all of the above.

D is the correct answer. Glaucoma is detected during a comprehensive eye exam that includes a visual acuity test, dilated eye exam, tonometry, pachymetry, and visual field test.

3. Glaucoma can occur in

A. one eye.
B. both eyes.
C. one or both eyes.

C is the correct answer. Glaucoma can occur in one or both eyes.

4. Without treatment, people with glaucoma will slowly lose their

A. peripheral, or side vision.
B. central vision.
C. both peripheral and central vision.

C is the correct answer. Without treatment, people with glaucoma will slowly lose their peripheral, or side vision. They seem to be looking through a tunnel. Over time, central or straight-ahead vision may decrease until no vision remains.


Treatment

Although open-angle glaucoma cannot be cured, it can usually be controlled. While treatments may save remaining vision, they do not improve sight already lost from glaucoma.

The most common treatments for glaucoma are medication and surgery.

Medications for glaucoma may be either in the form of eye drops or pills. Some drugs reduce pressure by slowing the flow of fluid into the eye. Others help to improve fluid drainage.

For most people with glaucoma, regular use of medications will control the increased fluid pressure. But, these drugs may stop working over time. Or, they may cause side effects. If a problem occurs, the eye care professional may select other drugs, change the dose, or suggest other ways to deal with the problem.

Laser surgery is another treatment for glaucoma. During laser surgery, a strong beam of light is focused on the part of the anterior chamber where the fluid leaves the eye. This results in a series of small changes that makes it easier for fluid to exit the eye. Over time, the effect of laser surgery may wear off. Patients who have this form of surgery may need to keep taking glaucoma drugs.

Researchers are studying the causes of glaucoma and are looking for ways to improve its diagnosis and treatment. For instance, the National Eye Institute, or NEI, is funding a number of studies to find out what causes fluid pressure to increase in the eye.

By learning more about this process, doctors may be able to find the exact cause of the disease and better learn how to prevent and treat it. The NEI also supports clinical trials of new drugs and surgical techniques that show promise against glaucoma.

Studies have shown that the early detection and treatment of glaucoma, before it causes major vision loss, is the best way to control the disease. So, if you fall into one of the high-risk groups for the disease, make sure to have your eyes examined through dilated pupils at least every two years by an eye care professional.

Quiz

1. The most common treatments for glaucoma include all of the following except

A. medications.
B. laser surgery.
C. conventional surgery.
D. eye exercises.

D is the correct answer. Although open-angle glaucoma cannot be cured, it can usually be controlled with medications, laser surgery, or conventional surgery.

2. Glaucoma medications help

A. reduce pressure in the eye.
B. improve optic nerve health.
C. dilate the pupils.

A is the correct answer. Glaucoma drugs reduce pressure in the eye by slowing the flow of fluid into the eye.

3. Over time, the effect of laser surgery may

A. wear off.
B. get stronger.
C. cause dry eye.

A is the correct answer. Over time, the effect of laser surgery may wear off. Patients who have this form of surgery may need to keep taking glaucoma drugs.

4. The best way to control glaucoma is to

A. seek early detection and treatment.
B. avoid reading in dimly lit places.
C. take vitamin supplements.

A is the correct answer. Studies have shown that the early detection and treatment of glaucoma, before it causes major vision loss, is the best way to control the disease.


Frequently Asked Questions

1. What is glaucoma?

What is Glaucoma?Glaucoma is a group of diseases that can damage the eye's optic nerve and result in vision loss and blindness. The most common form of the disease is open-angle glaucoma. With early treatment, you can often protect your eyes against serious vision loss.

2. What is the optic nerve?

The optic nerve is a bundle of more than 1 million nerve fibers. It connects the retina to the brain.

3. What is open-angle glaucoma?

Eye anatomyOpen-angle glaucoma is the most common form of glaucoma. In the normal eye, the clear fluid leaves the anterior chamber at the open angle where the cornea and iris meet. When the fluid reaches the angle, it flows through a spongy meshwork, like a drain, and leaves the eye.

Sometimes, when the fluid reaches the angle, it passes too slowly through the meshwork drain, causing the pressure inside the eye to build. If the pressure damages the optic nerve, open-angle glaucoma -- and vision loss -- may result.

4. Does increased eye pressure mean that I have glaucoma?

Not necessarily. Increased eye pressure means you are at risk for glaucoma, but does not mean you have the disease. A person has glaucoma only if the optic nerve is damaged. If you have increased eye pressure but no damage to the optic nerve, you do not have glaucoma. However, you are at risk. Follow the advice of your eye care professional.

5. Will I develop glaucoma if I have increased eye pressure?

Not necessarily. Not every person with increased eye pressure will develop glaucoma. Some people can tolerate higher eye pressure better than others. Also, a certain level of eye pressure may be high for one person but normal for another.

6. Can I develop glaucoma without an increase in my eye pressure?

Yes. Glaucoma can develop without increased eye pressure. This form of glaucoma is called low-tension or normal-tension glaucoma. It is not as common as open-angle glaucoma.

7. Who is at risk for open-angle glaucoma?

Anyone can develop glaucoma. Some people are at higher risk than others. They include

  • African-Americans over age 40
  • everyone over age 60, especially Mexican-Americans
  • people with a family history of glaucoma.
8. How can I prevent the disease from occurring?

At this time, we do not know how to prevent glaucoma. However, studies have shown that the early detection and treatment of glaucoma, before it causes major vision loss, is the best way to control the disease. So, if you fall into one of the high-risk groups for the disease, make sure to have your eyes examined through dilated pupils every two years by an eye care professional.

9. What are the symptoms of glaucoma?

Normal visionAt first, open-angle glaucoma has no symptoms. It causes no pain. Vision seems normal.

Distorted visionWithout treatment, people with glaucoma will slowly lose their peripheral, or side vision. They seem to be looking through a tunnel. Over time, straight-ahead vision may decrease until no vision remains.

10. How is glaucoma detected?

What is Glaucoma?Glaucoma is detected through a comprehensive eye exam that includes a visual acuity test, visual field test, dilated eye exam, tonometry, and pachymetry.

11. Can glaucoma be cured?

No. There is no cure for glaucoma. Vision lost from the disease cannot be restored.

12. Can glaucoma be treated?

Yes. Immediate treatment for early stage, open-angle glaucoma can delay progression of the disease. That's why early diagnosis is very important. Glaucoma treatments include medicines, laser surgery, conventional surgery, or a combination of any of these. While these treatments may save remaining vision, they do not improve sight already lost from glaucoma.

13. What can I do to protect my vision?

What is Glaucoma?If you are taking medicines for glaucoma, be sure to take them every day as directed by your eye care professional. People at risk for glaucoma should have a dilated eye exam at least every two years. If you have been diagnosed, you may need to see your eye care professional more often.

14. What can I do if I already have lost some vision from glaucoma?

If you have lost some sight from glaucoma, ask your eye care professional about low vision services and devices that may help you make the most of your remaining vision.

Ask for a referral to a specialist in low vision. Many community organizations and agencies offer information about low vision counseling, training, and other special services for people with visual impairments. A nearby school of medicine or optometry may provide low vision services.

15. What research is being done?

Through studies in the laboratory and with patients, the National Eye Institute is seeking better ways to detect, treat, and prevent vision loss in people with glaucoma. For example, researchers have discovered genes that could help explain how glaucoma damages the eye.

16. What should I do for a family member or friend who may be at risk of glaucoma?

Encourage them to have a comprehensive dilated eye exam at least once every two years. Remember -- lowering eye pressure in glaucoma's early stages slows progression of the disease and helps save vision.

17. Does Medicare cover the cost of an annual comprehensive eye exam?

Yes, in certain cases. Medicare covers an annual comprehensive dilated eye exam for some people at high risk for glaucoma. These people include those with diabetes, those with a family history of glaucoma, and African-Americans age 50 and older.

18. Where can I get more information?

National Eye Institute
National Institutes of Health
2020 Vision Place
Bethesda, MD 20892-3655
301-496-5248
E-mail: 2020@nei.nih.gov
www.nei.nih.gov

The Glaucoma Foundation
80 Maiden Lane, Suite 1206
New York, NY 10038
1-800-452-8266

Glaucoma Research Foundation
251 Post Street, Suite 600
San Francisco, CA 94108
1-800-826-6693


Topic last reviewed: 14 September 2009
Topic first published: 15 June 2005