Peripheral Artery Disease (P.A.D.)

Frequently Asked Questions

2. What causes P.A.D.?

The most common cause of P.A.D. is atherosclerosis, a buildup of plaque in the arteries. Over time, plaque can harden and narrow the arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body.

The exact cause of atherosclerosis isn't known. The disease may start if certain factors damage the inner layers of the arteries. These factors include

  • smoking
  • high blood pressure
  • high amounts of certain fats and cholesterol in the blood
  • high amounts of sugar in the blood due to insulin resistance or diabetes.